How Cbd Works: Understanding the Endocannabinoid System

CBD: Stimulating the Endocannabinoid System

CBD is a molecule from the genus Cannabis, which has many beneficial therapeutic effects, proven by science over time. The real effect of CBD is mediated by the endocannabinoid system, a complex cluster of receptors scattered throughout our body, which mediate various important chemical reactions every second.

All people have an endocannabinoid system, and this is essential for the proper functioning of our body. In fact, this system is closely linked to the control of inflammation, pain, memory and stress.

CBD and 60 Ways to Work

CBD, as well as THC, can mimic the structure and behavior of endocannabinoids present in our body, so they have the same ability to activate CB1 and CB2 receptors. Even so, both CBD and THC have slight differences in their molecular structure, so each one ends up activating a specific receptor. This is the reason why THC has so many psychotropic effects, while CBD is known for its multiple natural benefits.

In fact, CBD does not interact well with endocannabinoid receptors, but it can activate more than 60 molecular pathways, unleashing a host of chemical reactions in the body, all of which have a positive effect.

Some of the direct effects of CBD are:

Serotonin Stimulation:

Serotonin is the so-called "happiness hormone", able to increase mood and regulate the circadian cycle, as well as certain motor and cognitive functions. Several studies show that high doses of CBD can increase serotonin levels from the direct stimulation of serotonergic receptors (5-HT1A).

Controlling pain and inflammation:

from several different routes, involving receptors such as TRPV1, CBD can regulate the nociceptive impulses of the neurons of the peripheral nervous system, limiting the transmission of signals to the brain, so that despite feel pain, our brain would not be able to manifest it.

In addition, these same receptors also regulate the signaling that occurs in the various processes of inflammation, so we can expect an alleviation of the inflammatory processes that would help in certain diseases. Nowadays, CBD is widely used for the control of chronic pain, especially those related to joint pain(such as osteoarthritis or rheumatic arthritis).

Anxiolytic:

Without a doubt, for a long time the CBD has been considered as a powerful anxiolytic, but a few years ago it is that the reason was discovered. CBD interacts with the GABA receptors in our brain, which are involved in central nervous system inhibition and control reactions.

With stimulation of these receptors, studies show that CBD can control various psychiatric disorders related to anxiety, including CBD can be used as an anticonvulsant in certain cases. The use of this derivative of Cannabis can benefit many people suffering from panic disorders.

Anticancer Effect:

Through the activation of certain receptor groups, such as the PPAR Gamma Receptors, it appears that CBD can inhibit the growth and proliferation of tumor cells. Although they are promising effects, undoubtedly, they need more studies to verify and clarify a bit the underlying mechanism after the stimulation of these receptors.

We are still trying to fully understand the way in which CBD works and the presence of endocannabinoid system receptors. An example of how far we are to understand the system well lies with diabetes. It seems that the stimulation of CB2 receptors in the pancreas could omit the progression of type 1 diabetes mellitus, but we are not even able to confirm the presence of receptors at that level.

Even so, this phytocannabinoid is helping countless people around the world, not only to manage the pathologies but the symptoms that each one can trigger. Without a doubt, he deserves all the attention he is receiving and has a promising future in the field of medicine.

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